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2. ICD-10 Codes
3. Chapter - M00-M99
4. Section - M30-M36
5. Category - M35
6. M35.81

M35.81 - Multisystem inflammatory syndrome

• Applicable to Multisystem inflammatory syndrome
• The 2025 edition of ICD10-CM M35.81 became effective on October 1, 2024.
• This is the American ICD10-CM version of M35.81 - other international versions of ICD10 M35.81 may differ.
• M35.81 is a Billable / Specific ICD10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

Code Additional Code:

• code, if applicable, for:
• exposure to COVID-19 or SARS-CoV-2 infection (Z20.822)
• personal history of COVID-19 (Z86.16)
• post COVID-19 condition (U09.9)

• MIS-A
• MIS-C
• Multisystem inflammatory syndrome in adults
• Multisystem inflammatory syndrome in children
• Pediatric inflammatory multisystem syndrome
• PIMS

codefirst

• , if applicable, COVID-19 (U07.1)

codeAlso

• any associated complications such as:
• acute hepatic failure (K72.0-)
• acute kidney failure (N17.-)
• acute myocarditis (I40.-)
• acute respiratory distress syndrome (J80)
• cardiac arrhythmia (I47-I49.-)
• pneumonia due to COVID-19 (J12.82)
• severe sepsis (R65.2-)
• viral cardiomyopathy (B33.24)
• viral pericarditis (B33.23)

The following codes above M35.81 contain annotation back-references that may be applicable to M35.81:

• Chapter: M00-M99 - Diseases of the musculoskeletal system and connective tissue
• Section: M30-M36 - Systemic connective tissue disorders
• Category: M35 - Other systemic involvement of connective tissue

Browse other similar CM codes:

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.