C84.7
Anaplastic large cell lymphoma, ALK-negative
Clinical Classification Guidelines
Excludes Type 1
- primary cutaneous CD30-positive T-cell proliferations (C86.6-)
Medical Intelligence & Overview
Anaplastic large cell lymphoma, ALK-negative (ICD-10 code C84.7), is a type of non-Hodgkin lymphoma that affects the lymphatic system. It is characterized by the rapid growth of large, abnormal lymphocytes. Unlike ALK-positive variants, this form does not exhibit anaplastic lymphoma kinase gene rearrangements. It can occur in various parts of the body, primarily involving lymph nodes, but may also spread to other organs. Understanding this disease's nature helps in recognizing its impact and guiding appropriate medical care.
Causes & Symptoms
Clinical Causes: The exact cause of ALK-negative anaplastic large cell lymphoma is unknown. Genetic mutations or abnormalities in lymphocytes are believed to play a role. Certain environmental factors or exposures may contribute, but no definitive link has been established. It is not considered contagious and does not spread from person to person.
Key Symptoms: Painless swelling of lymph nodes, often in neck, armpits, or groin Fever that persists over time Unexplained weight loss Night sweats Fatigue or weakness Skin rashes or lumps if it affects the skin Breathing difficulties or cough if the lungs are involved Abdominal pain or swelling if organs like the spleen or liver are affected
Diagnostic & Treatment
Diagnosis Path: Diagnosing ALK-negative anaplastic large cell lymphoma involves several steps:
Treatment Protocols: Treatment options are tailored based on the stage and specific characteristics of the lymphoma:
Clinical Advice & FAQs
Billing Guidance
Is C84.7 a billable ICD-10 code?
Yes, C84.7 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report C84.7?
Clinical documentation must specify the nature of Anaplastic large cell lymphoma, ALK-negative and any associated comorbidities for accurate reporting.
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