C84.65
Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb
Clinical Classification Guidelines
Medical Intelligence & Overview
Anaplastic Large Cell Lymphoma, ALK-positive (ICD-10 Code C84.65), is a type of non-Hodgkin lymphoma characterized by the abnormal growth of large lymphoid cells. It primarily affects lymph nodes, especially in the inguinal region (groin area) and lower limbs. This lymphoma is distinguished by the presence of the anaplastic large cell phenotype and positivity for the anaplastic lymphoma kinase (ALK) protein, which influences its behavior and response to treatment. Understanding this condition can help patients gain insight into the disease's nature and its management options.
Causes & Symptoms
Clinical Causes: Genetic mutations leading to abnormal ALK gene expression Chromosomal rearrangements involving the ALK gene Potential environmental factors, though specific causes are largely unknown Immunological factors that may influence the development of lymphoid cancers
Key Symptoms: Swelling or painless lumps in the inguinal (groin) region Lumps or swelling in the lower limbs Persistent fatigue or weakness Fever that doesn't go away Night sweats Unintentional weight loss Itching skin over affected areas Localized pain or discomfort in swollen lymph node areas
Diagnostic & Treatment
Diagnosis Path: Diagnosing anaplastic large cell lymphoma, ALK-positive, usually involves several steps:
Treatment Protocols: Treatment approaches for ALK-positive anaplastic large cell lymphoma typically include:
Clinical Advice & FAQs
Billing Guidance
Is C84.65 a billable ICD-10 code?
Yes, C84.65 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report C84.65?
Clinical documentation must specify the nature of Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb and any associated comorbidities for accurate reporting.
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