C83.79
Burkitt lymphoma, extranodal and solid organ sites
Clinical Classification Guidelines
Medical Intelligence & Overview
Burkitt lymphoma is a highly aggressive form of non-Hodgkin lymphoma characterized by rapid growth of cancerous lymphoid cells. This type of lymphoma often arises in the lymph nodes but can also originate in other parts of the body, such as the stomach, intestines, or other solid organs. The ICD-10 code C83.79 is used specifically to classify cases where Burkitt lymphoma manifests outside the lymph nodes, involving extranodal and solid organ sites, emphasizing its unique clinical presentation and treatment considerations.
Causes & Symptoms
Clinical Causes: Genetic mutations, such as the translocation of MYC gene (most commonly t(8;14)) Infections, notably Epstein-Barr Virus (EBV), particularly in endemic regions Immunodeficiency conditions, including HIV/AIDS Environmental factors, although less well understood Previous history of certain cancers or treatments that weaken the immune system
Key Symptoms: Rapid swelling of affected areas, such as the abdomen, jaw, or face Unexplained weight loss Persistent fever and night sweats Abdominal pain or swelling Digestive issues, like nausea or vomiting if gastrointestinal involvement occurs Fatigue or weakness Signs of infection or bleeding, depending on tumor location
Diagnostic & Treatment
Diagnosis Path: Biopsy of the affected tissue to identify cancerous lymphoid cells Immunophenotyping to determine specific cell markers Imaging studies such as CT scans, PET scans, or MRI to assess the extent of the disease Laboratory tests including blood counts and organ function tests Bone marrow biopsy in cases with suspected marrow involvement Molecular studies to detect genetic translocations like MYC gene rearrangement
Treatment Protocols: Intensive chemotherapy protocols tailored to the patient's age and health status Targeted therapies and immunotherapy in certain cases Supportive care to manage side effects of treatment and nutritional needs Radiation therapy, which may be used for localized tumors Intrathecal chemotherapy if there is central nervous system involvement Close monitoring for treatment response and potential relapse
Clinical Advice & FAQs
Billing Guidance
Is C83.79 a billable ICD-10 code?
Yes, C83.79 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report C83.79?
Clinical documentation must specify the nature of Burkitt lymphoma, extranodal and solid organ sites and any associated comorbidities for accurate reporting.
Cite this Clinical Reference