C83.36
Diffuse large B-cell lymphoma, intrapelvic lymph nodes
Clinical Classification Guidelines
Medical Intelligence & Overview
Diffuse large B-cell lymphoma (DLBCL) is a type of non-Hodgkin lymphoma characterized by the rapid growth of abnormal B-cells, a type of white blood cell involved in the immune response. When this lymphoma occurs in the intrapelvic lymph nodes, it specifically affects lymph nodes located within the pelvic region. This condition requires careful diagnosis and management, as it can involve a significant internal area and may affect overall health.
Causes & Symptoms
Clinical Causes: Genetic mutations affecting B-cells leading to uncontrolled growth Immune system dysfunction or suppression Infections linked to lymphoma development, such as Epstein-Barr virus (EBV) Previous exposure to radiation or certain chemotherapy treatments Family history of lymphomas or other hematologic malignancies
Key Symptoms: Swelling or painless lump in the pelvic area Abdominal pain or discomfort Unexplained weight loss Persistent fever or night sweats Fatigue or general weakness Difficulty urinating or bowel movements if the lymph nodes press on nearby organs
Diagnostic & Treatment
Diagnosis Path: Medical history review and physical examination focusing on swelling or palpable masses in the pelvic area Imaging studies such as computed tomography (CT) scans, positron emission tomography (PET) scans, or magnetic resonance imaging (MRI) to visualize lymph node involvement Biopsy of affected lymph nodes to confirm the presence of malignant B-cells and identify characteristic features of DLBCL Laboratory tests including blood counts and bone marrow biopsies to assess the extent of disease Additional tests like flow cytometry and molecular studies for detailed analysis
Treatment Protocols: Chemotherapy, typically using a combination regimen such as R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) Targeted therapy with monoclonal antibodies like rituximab to specifically attack B-cells Radiation therapy may be employed in localized disease or for residual tumor control Stem cell transplantation in certain cases to improve long-term outcomes Supportive care measures to manage symptoms and reduce side effects of treatments
Clinical Advice & FAQs
Billing Guidance
Is C83.36 a billable ICD-10 code?
Yes, C83.36 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report C83.36?
Clinical documentation must specify the nature of Diffuse large B-cell lymphoma, intrapelvic lymph nodes and any associated comorbidities for accurate reporting.
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