ICD-10-PCS Billable Code

07YP0Z0

Transplantation Spleen to Allogeneic with No Device, Open Approach

Procedural Specifications

Clinical Axis Detail Definition
Section0 Medical and Surgical
Body System7 Lymphatic and Hemic Systems
OperationY Transplantation
Body PartP Spleen
Approach0 Open
DeviceZ No Device
Qualifier0 Allogeneic

Operation Definition

Putting in or on all or a portion of a living body part taken from another individual or animal to physically take the place and/or function of all or a portion of a similar body part

Procedure Overview

Transplantation in this body system means taking living tissue from another person and placing it in a patient to take over the function of a missing or nonfunctional native structure, and the clearest example is thymus tissue transplantation for infants born with complete DiGeorge syndrome. These children lack a functioning thymus, the organ responsible for maturing T cells, which leaves them without a working immune system. Surgeons implant cultured thymus tissue from a donor into the recipient's body, where it can begin to support the development of the child's own immune cells over time.

This is a highly specialized procedure performed at a small number of centers, reserved for a rare and serious immune deficiency, and it illustrates how transplantation in the lymphatic and hemic system focuses on restoring an entire biological function rather than simply repairing damaged tissue.

Anatomy & Axis Detail

Spleen

Splenic transplantation is a rare procedure, generally reserved for research settings or highly selected cases of severe hereditary immunodeficiency or hematologic disease where restoring splenic immune function is judged to outweigh the risks of allograft rejection and lifelong immunosuppression. Unlike splenic autotransplantation of preserved tissue after traumatic splenectomy, which reimplants a patient's own fragments to preserve some immune reserve, this root operation and body part combination describes replacement with all or part of a donor spleen. The procedure is technically demanding given the organ's vascular fragility and the need for arterial and venous anastomoses, and it remains far less established than transplantation of solid organs such as the kidney or liver. Coding should reflect the source of the graft and confirm that native splenic tissue, if present, is not simultaneously excised under a separate root operation.

Approach: Open

Open approach means the surgeon cuts through skin, mucous membrane, or other tissue layers to physically expose the target site to view before performing the procedure. It gives direct visualization and hands-on access, distinguishing it from Percutaneous approaches where instruments pass through a small puncture without exposing the site. Open is typical for procedures needing wide access, such as most laparotomies.

Qualifier: Allogeneic

This qualifier denotes an allogeneic tissue substitute, meaning material derived from another individual of the same species rather than the patient's own tissue. It is distinguished from the syngeneic qualifier, which applies only to genetically identical donors, and from zooplastic, which denotes tissue sourced from a different species entirely.

Coding & Documentation

Coders should look for explicit documentation that donor tissue, such as thymus, was implanted to take over the function of the patient's own nonfunctioning or absent structure, along with confirmation that the tissue came from another individual rather than the patient's own body. A frequent point of confusion is failing to distinguish an allogeneic donor source, which supports Transplantation, from autologous tissue relocated within the same patient, which would be coded differently. The donor relationship and the intent to replace lost function must both be clearly stated in the record.

Commonly Confused With

SupplementSupplement is the nearby family that instead reinforces existing tissue with biological or synthetic material rather than replacing an entire nonfunctioning structure with living donor tissue, so the key distinction is whether native function is being augmented or substituted outright.
ReplacementReplacement is a related concept used elsewhere in the body when a body part is physically substituted, but in this system it would apply to nonliving substitutes rather than the living donor tissue that defines Transplantation.

Procedural Guidance & FAQs

Coding Accuracy

Is 07YP0Z0 a billable procedure?

Yes, 07YP0Z0 is a complete, 7-character procedural specification that is acceptable for hospital claim reimbursement.

Technical Axis

What approach is used for 07YP0Z0?

This procedure utilizes the Open approach, mapping to the 5th character in the PCS axis.

Metadata Tags

allogeneic transplantation spleen