T39.31

Clinical Causes: Accidental or intentional overdose of propionic acid derivative medications such as ibuprofen or naproxen. Taking higher doses of these medications than recommended. Misuse or overuse, particularly in individuals with underlying health conditions. Inadvertent ingestion of medications containing propionic acid derivatives, especially in children. Prolonged use beyond recommended duration without medical supervision.

Key Symptoms: Nausea and vomiting Stomach pain or discomfort Gastrointestinal bleeding or black, tarry stools Signs of kidney problems like decreased urine output or swelling Dizziness or lightheadedness Hearing loss or ringing in the ears Allergic reactions such as rash, itching, or swelling Confusion or drowsiness in severe cases

Diagnosis Path: Diagnosis typically involves reviewing the patient’s medical history, medication intake, and presenting symptoms. Blood tests may be conducted to detect medication levels, assess kidney and liver function, and identify any signs of internal bleeding or toxicity. Urinalysis can help evaluate kidney health, and additional imaging tests may be ordered if complications are suspected.

Treatment Protocols: Treatment will depend on the severity of the poisoning or side effects. Common approaches include: - **Supportive Care:** Monitoring vital signs, ensuring adequate hydration, and correcting electrolyte imbalances. - **Gastric Decontamination:** Sometimes activated charcoal is administered to reduce medication absorption if the ingestion was recent. - **Medications:** Use of specific antidotes is not typical; instead, medications might be used to manage symptoms like pain, nausea, or blood pressure issues. - **Monitoring:** Ongoing assessment of kidney and liver function, and observation for any signs of worsening condition. - **Hospitalization:** Severe cases may require admission for intensive monitoring and supportive care, including dialysis if kidney failure occurs.