T39.392

Clinical Causes: Intentional overdose of NSAIDs as an act of self-harm Mental health issues such as depression or suicidal ideation Accidental ingestion in individuals with cognitive impairments or lack of awareness Misuse of NSAID medications for non-medical reasons Lack of proper medication management or supervision

Key Symptoms: Gastrointestinal symptoms such as nausea, vomiting, or abdominal pain Gastrointestinal bleeding or ulcers in severe cases Dizziness or lightheadedness Signs of kidney impairment like decreased urine output Symptoms of blood clotting abnormalities, including easy bruising or bleeding In some cases, neurological symptoms like confusion or altered mental status

Diagnosis Path: The diagnosis of NSAID poisoning involves a combination of medical history, physical examination, and laboratory tests. Healthcare providers will assess recent medication intake, especially in cases of suspected intentional overdose. Blood tests are used to evaluate the levels of NSAIDs in the bloodstream, kidney function, blood counts, and indicators of organ damage. Urinalysis and imaging studies may be performed if complications such as bleeding or organ injury are suspected. Mental health evaluation is also an important part of the diagnosis process in cases of intentional self-harm.

Treatment Protocols: Gastrointestinal decontamination procedures like activated charcoal to limit absorption if within the appropriate timeframe Supportive care including intravenous fluids and monitoring of vital signs Management of specific symptoms such as nausea or pain Treatment of any organ damage, including dialysis if kidney failure occurs Monitoring and correction of acid-base imbalances and electrolyte disturbances Psychological support and mental health intervention to address underlying issues related to self-harm