L70.1

Clinical Causes: Hormonal imbalances, particularly androgens, which increase oil production in the skin Genetic predisposition, making some individuals more susceptible Infections or bacterial overgrowth within blocked pores Use of certain medications, such as anabolic steroids or corticosteroids Underlying medical conditions, such as endocrine disorders

Key Symptoms: Large, inflamed nodules and cysts deeply embedded in the skin Multiple interconnected abscesses that form interconnected lesions Presence of 'bridge-like' scars and pitted scars after lesions heal Widespread skin involvement, particularly on the back, chest, and buttocks Pain and tenderness in affected areas Possible discharge of pus from cysts

Diagnosis Path: Diagnosis of acne conglobata is primarily clinical, based on physical examination of skin lesions. A healthcare provider assesses the pattern, severity, and distribution of acne lesions. When necessary, additional assessments such as bacterial cultures or hormonal evaluations may be performed to identify underlying causes or contributing factors. Skin biopsy is rarely needed but can help rule out other skin conditions if diagnosis is uncertain.

Treatment Protocols: Oral antibiotics to control bacterial growth and reduce inflammation Hormonal therapy, such as oral contraceptives or anti-androgens, especially in women Retinoids, including isotretinoin, which help decrease oil production and promote skin healing Immunomodulating treatments for severe cases Surgical procedures, like drainage or laser therapy, to remove cysts and scars Good skincare practices, including gentle cleansing and avoiding comedogenic products