I67.850
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
Clinical Classification Guidelines
Inclusion Terms
- CADASIL
Code Also
- any associated diagnoses, such as:
- epilepsy (G40.-)
- stroke (I63.-)
- vascular dementia (F01.-)
Medical Intelligence & Overview
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a hereditary neurological condition that affects the small blood vessels in the brain. It is classified under the ICD-10 code I67.850. This disorder leads to issues with blood flow in small arteries, causing damage to brain tissue, which can result in strokes, cognitive decline, and other neurological symptoms. Being a genetic condition, CADASIL is inherited and can affect individuals across different age groups, although symptoms often begin in middle age.
Causes & Symptoms
Clinical Causes: Genetic mutation: CADASIL is caused by mutations in the NOTCH3 gene, which is essential for maintaining the health of blood vessel walls in the brain. Inheritance pattern: It follows an autosomal dominant pattern, meaning only one copy of the altered gene from an affected parent can cause the disorder. Family history: A family history of strokes, migraines with aura, or early cognitive decline increases the likelihood of developing CADASIL.
Key Symptoms: Migraine headaches, often with aura Repeated strokes or transient ischemic attacks (TIAs) Progressive cognitive decline and dementia Mood disorders such as depression Gait disturbances and weakness Difficulty with coordination and balance Changes in behavior and personality
Diagnostic & Treatment
Diagnosis Path: Diagnosing CADASIL involves a combination of clinical evaluation and laboratory tests. Healthcare providers may perform the following:
Treatment Protocols: There is currently no cure for CADASIL, but treatment aims to manage symptoms and reduce complications. Healthcare providers may recommend:
Clinical Advice & FAQs
Billing Guidance
Is I67.850 a billable ICD-10 code?
Yes, I67.850 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report I67.850?
Clinical documentation must specify the nature of Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy and any associated comorbidities for accurate reporting.
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