O41.12

Clinical Causes: Ascension of bacteria from the vagina or cervix into the uterus, often during or near labor Premature rupture of membranes (water breaking early before labor begins) Prolonged labor, which can increase the risk of bacteria entering the uterus Multiple cervical exams during labor, providing pathways for bacteria Presence of intrauterine devices (IUDs) or other foreign bodies Low immune system function, which makes infections more likely

Key Symptoms: Fever and chills during labor Uterine tenderness or unusual uterine contractions Foul-smelling amniotic fluid Increased maternal heart rate (tachycardia) Fetal distress or abnormal fetal heart rate patterns General feelings of illness or discomfort Elevated maternal white blood cell count (detected through tests)

Diagnosis Path: Diagnosing chorioamnionitis involves a combination of clinical assessments and laboratory tests. Healthcare providers typically evaluate symptoms such as maternal fever and uterine tenderness. They may also analyze amniotic fluid obtained via amniocentesis or during labor. Additionally, blood tests can reveal signs of infection, including increased white blood cell count. Monitoring fetal well-being through fetal heart rate monitoring is also an essential part of diagnosis.

Treatment Protocols: Treatment usually involves the administration of antibiotics to combat the infection promptly. Women with chorioamnionitis often require close monitoring of both mother and baby during labor. In some cases, delivery may be expedited to prevent further complications, especially if the infection is severe or if the pregnancy has reached a stage where immediate delivery is safe. Post-delivery, both mother and baby are monitored for any signs of ongoing infection or related complications. Antibiotic therapy may continue after delivery if needed.