A31.2
Disseminated mycobacterium avium-intracellulare complex (DMAC)
Clinical Classification Guidelines
Inclusion Terms
- MAC sepsis
Medical Intelligence & Overview
Disseminated Mycobacterium avium-intracellulare complex (MAC) infection, classified under ICD-10 code A31.2, is a serious bacterial condition caused by the spread of MAC bacteria throughout the body. This infection primarily affects individuals with weakened immune systems, such as those with HIV/AIDS or undergoing immunosuppressive therapy. MAC sepsis can lead to widespread organ involvement, making it a significant health concern requiring prompt diagnosis and management.
Causes & Symptoms
Clinical Causes: Infection with Mycobacterium avium-intracellulare bacteria, typically acquired via environmental sources like soil and water Immunodeficiency, particularly in individuals with HIV/AIDS, organ transplant recipients, or those on immunosuppressive medications Progression from localized MAC infections in the lungs or other tissues to a disseminated form Inadequate immune response allowing bacteria to spread through the bloodstream and affect multiple organs
Key Symptoms: Fever and chills Night sweats Unintentional weight loss Fatigue and weakness Swollen lymph nodes Muscle pain and joint inflammation Persistent diarrhea or abdominal discomfort Anemia and anemia-related symptoms Signs of organ-specific involvement, such as liver or spleen enlargement
Diagnostic & Treatment
Diagnosis Path: Diagnosis of disseminated MAC infection involves a combination of blood tests, cultures, and imaging studies. Blood cultures are essential in detecting MAC bacteria circulating in the bloodstream. Additionally, tissue biopsies, chest X-rays, or CT scans may reveal organ involvement. Laboratory tests typically include acid-fast staining and molecular assays to identify MAC species. Clinicians also consider the patient's immune status and clinical presentation to confirm the diagnosis.
Treatment Protocols: Treatment strategies for disseminated MAC infection involve a prolonged course of multiple antibiotics to eradicate the bacteria. Common regimens include:
Clinical Advice & FAQs
Billing Guidance
Is A31.2 a billable ICD-10 code?
Yes, A31.2 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report A31.2?
Clinical documentation must specify the nature of Disseminated mycobacterium avium-intracellulare complex (DMAC) and any associated comorbidities for accurate reporting.
Cite this Clinical Reference