Z40.02

Clinical Causes: Genetic mutations, such as BRCA1 or BRCA2 gene mutations, that increase ovarian cancer risk A strong family history of ovarian or breast cancer Presence of inherited cancer syndromes Personal history of ovarian, fallopian tube, or primary peritoneal cancers Preventive measure in women at high risk of developing ovarian cancer

Key Symptoms: Usually, there are no symptoms leading up to the prophylactic removal, as it is performed preventively In some cases, women might experience symptoms related to the ovaries if they are enlarged or inflamed, such as pelvic pain, bloating, or pressure Postoperative symptoms may include pain, discomfort, or fatigue related to recovery from surgery

Diagnosis Path: The decision to proceed with prophylactic ovary removal is based on detailed medical assessments, including genetic testing, family medical history, and risk evaluation. Imaging studies such as ultrasound, MRI, or CT scans might be used to assess ovarian status before surgery. The process involves thorough consultation between a woman and her healthcare team to evaluate the benefits and potential risks of the procedure.

Treatment Protocols: The primary treatment in this context is surgical removal of one or both ovaries (oophorectomy). This procedure can be performed through minimally invasive techniques like laparoscopy or via open surgery. Preoperative preparations include counseling, imaging studies, and discussing the potential impact on hormonal balance. Postoperative care involves managing pain, monitoring for complications, and providing guidance on life after ovarian removal, such as hormone replacement therapy considerations if indicated. The goal of this preventive measure is to significantly reduce the risk of developing ovarian cancer in women at high risk.