D56.5
Hemoglobin E-beta thalassemia
Clinical Classification Guidelines
Excludes Type 1
- beta thalassemia (D56.1)
- beta thalassemia minor (D56.3)
- beta thalassemia trait (D56.3)
- delta-beta thalassemia (D56.2)
- delta-beta thalassemia trait (D56.3)
- hemoglobin E disease (D58.2)
- other hemoglobinopathies (D58.2)
- sickle-cell beta thalassemia (D57.4-)
Medical Intelligence & Overview
Hemoglobin E-beta thalassemia is a blood disorder characterized by a deficiency in the production of hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body. This condition results from a combination of two genetic traits: Hemoglobin E and beta thalassemia. People with this disorder may experience a range of symptoms from mild anemia to more severe health issues, depending on the severity of the disease. Understanding this condition can help individuals and caregivers recognize symptoms and seek appropriate medical care.
Causes & Symptoms
Clinical Causes: Inherited genetic mutation affecting hemoglobin production Inheritance from both parents carrying the Hemoglobin E and beta thalassemia traits A combination of genetic factors leading to abnormal hemoglobin formation
Key Symptoms: Mild to moderate anemia, leading to fatigue and weakness Pale or yellowish skin (jaundice) Swelling in the abdomen or face Dark-colored urine Delayed growth and development in children Enlarged spleen or liver Bone deformities in severe cases Increased susceptibility to infections
Diagnostic & Treatment
Diagnosis Path: Diagnosis typically involves blood tests that evaluate hemoglobin levels and identify abnormal hemoglobin variants. These tests include:
Treatment Protocols: While there is no universal cure for Hemoglobin E-beta thalassemia, various treatments aim to manage symptoms and prevent complications:
Clinical Advice & FAQs
Billing Guidance
Is D56.5 a billable ICD-10 code?
Yes, D56.5 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report D56.5?
Clinical documentation must specify the nature of Hemoglobin E-beta thalassemia and any associated comorbidities for accurate reporting.
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