N07.6
Hereditary nephropathy, not elsewhere classified with dense deposit disease
Clinical Classification Guidelines
Inclusion Terms
- Hereditary nephropathy, not elsewhere classified with C3 glomerulopathy with dense deposit disease
- Hereditary nephropathy, not elsewhere classified with membranoproliferative glomerulonephritis, type 2
Medical Intelligence & Overview
Hereditary nephropathy with dense deposit disease is a rare inherited kidney disorder characterized by the abnormal deposits in the glomeruli, the tiny filtering units of the kidneys. This condition belongs to a group of diseases known as C3 glomerulopathies, which involve immune system components leading to kidney damage. It is a hereditary condition, meaning it can be passed down through families, and it often manifests through progressive kidney dysfunction.
Causes & Symptoms
Clinical Causes: Genetic mutations affecting the complement system, particularly the regulation of the C3 protein Inheritance patterns that can be autosomal dominant or autosomal recessive Family history of similar kidney conditions
Key Symptoms: Hematuria (blood in the urine) Proteinuria (excess protein in the urine) High blood pressure Reduced kidney function, which may progress to kidney failure Swelling (edema), especially in the legs, ankles, or around the eyes Fatigue and weakness due to impaired kidney function
Diagnostic & Treatment
Diagnosis Path: Diagnosing hereditary nephropathy with dense deposit disease involves a combination of clinical evaluations and laboratory tests. Kidney biopsy is pivotal, revealing characteristic dense deposits in the glomeruli under electron microscopy. Additional tests may include blood tests to assess kidney function, urinalysis to detect protein and blood in urine, and genetic testing to identify specific mutations linked to the disease. Imaging studies such as ultrasound can evaluate kidney size and exclude other causes of renal impairment.
Treatment Protocols: There is no definitive cure for hereditary nephropathy with dense deposit disease. Management focuses on controlling symptoms and slowing disease progression. Treatment approaches may include:
Clinical Advice & FAQs
Billing Guidance
Is N07.6 a billable ICD-10 code?
Yes, N07.6 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report N07.6?
Clinical documentation must specify the nature of Hereditary nephropathy, not elsewhere classified with dense deposit disease and any associated comorbidities for accurate reporting.
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