T37.4

Clinical Causes: Overdose of anthelminthic medications due to miscalculation or accidental ingestion Adverse reactions from sensitivity or allergy to specific anthelminthic drugs Use of expired or improperly stored medications leading to increased toxicity Underdosing resulting in ineffective treatment and potential parasite resistance Incorrect administration or dosing schedules prescribed by healthcare providers Combination of medications that may increase adverse effects Unsupervised self-medication without proper diagnosis or guidance

Key Symptoms: Nausea and vomiting Abdominal pain or cramping Diarrhea or constipation Dizziness or vertigo Skin rash or itching Fever and chills Muscle weakness or fatigue Signs of liver or kidney dysfunction (such as jaundice or abnormal blood tests) Severe allergic reactions like swelling or difficulty breathing in rare cases

Diagnosis Path: Diagnosing poisoning or adverse effects of anthelminthics involves a combination of reviewing patient history, medication usage, and presenting symptoms. Laboratory tests such as blood counts, liver and kidney function tests, and specific drug level measurements may be performed. Imaging studies are rarely needed but can be helpful in certain severe cases. A thorough clinical assessment helps determine whether symptoms are related to medication toxicity or adverse reactions.

Treatment Protocols: Management of poisoning or adverse effects includes supportive care, such as hydration, symptom relief, and close monitoring of vital signs. In cases of overdose, activated charcoal may be administered if appropriate and within a certain timeframe. Specific antidotes or interventions are rarely available for anthelminthic poisoning, so treating symptoms and preventing complications are key. Discontinuation of the offending medication and consultation with a healthcare professional are essential steps. In severe cases, hospitalization and intensive supportive measures may be necessary.