T38.5X3

Clinical Causes: Accidental ingestion of medications containing estrogens or progestogens, especially in children. Intentional overdose in an attempt to harm oneself. Misuse or abuse of hormone-based drugs for performance enhancement or other reasons. Incorrect dosage administration by healthcare providers or caregivers. Drug interactions that lead to elevated hormone levels.

Key Symptoms: Nausea and vomiting Breast tenderness or swelling Unusual uterine bleeding Headache or dizziness Mood changes or irritability Water retention and swelling Abdominal pain or cramps Skin changes, such as rash or acne Changes in menstrual cycle patterns Signs of hormone excess, including breast enlargement or vaginal bleeding

Diagnosis Path: Diagnosis of poisoning by estrogens and progestogens involves a combination of medical history assessment, physical examination, and laboratory testing. Healthcare providers may look for signs of hormone imbalance and verify exposure through blood tests measuring hormone levels. Additional diagnostic tools may include urine tests and assessment of any ingested medications or substances. The context of exposure, such as self-reporting or evidence of medication misuse, is vital for accurate diagnosis.

Treatment Protocols: Treatment depends on the severity and timing of exposure. It generally includes supportive care, such as monitoring vital signs, controlling symptoms like nausea or pain, and ensuring hydration. In cases of significant overdose, activated charcoal may be used to reduce absorption if ingestion was recent. Hospitalization might be necessary for severe poisoning, including hormone level stabilization and managing complications. Long-term treatment may involve hormone regulation and addressing any psychological factors related to intentional poisoning.