L74.512

Clinical Causes: Overactivity of sweat glands controlled by the sympathetic nervous system Genetic predisposition, with family members often experiencing similar symptoms Possible abnormalities in nerve signals that stimulate sweat glands

Key Symptoms: Persistent and excessive sweating on the palms, often occurring even without heat or physical activity Sweat that may be visible and can make handling objects difficult Clammy or moist feeling of the palms Potential skin issues such as irritation or fungal infections due to constant moisture Possible emotional effects like embarrassment or anxiety because of the sweating

Diagnosis Path: Diagnosis generally involves a detailed medical history and physical examination. A doctor may observe the extent and triggers of sweating and rule out other causes such as secondary hyperhidrosis linked to medical conditions. The Minor starch-iodine test can be used to identify areas with excessive sweating by applying a starch-iodine solution that turns blue-black when in contact with sweat.

Treatment Protocols: Topical medications containing aluminum chloride that reduce sweating Iontophoresis, a procedure that uses electrical currents to temporarily block sweat gland activity, especially effective for palms Botulinum toxin (Botox) injections that temporarily block nerve signals stimulating sweat glands Oral medications in certain cases, although these are typically reserved for severe cases due to potential side effects Lifestyle adjustments such as wearing breathable gloves or using absorbent materials Surgical options like endoscopic thoracic sympathectomy (ETS) may be considered for severe cases that do not respond to other treatments