ICD-10-CM Billable Code

B96.21

Shiga toxin-producing Escherichia coli [E. coli] [STEC] O157 as the cause of diseases classified elsewhere

Clinical Classification Guidelines

Inclusion Terms

  • E. coli O157:H- (nonmotile) with confirmation of Shiga toxin
  • E. coli O157 with confirmation of Shiga toxin when H antigen is unknown, or is not H7
  • O157:H7 Escherichia coli [E. coli] with or without confirmation of Shiga toxin-production
  • Shiga toxin-producing Escherichia coli [E. coli] O157:H7 with or without confirmation of Shiga toxin-production
  • STEC O157:H7 with or without confirmation of Shiga toxin-production

Medical Intelligence & Overview

ICD-10 code B96.21 refers to infections caused by specific strains of Escherichia coli (E. coli), particularly the O157 serotype that produces Shiga toxin. These bacteria can cause serious gastrointestinal illnesses and other complications. Recognizing the distinct features of this infection helps in understanding its severity and the importance of proper diagnosis and management.

Causes & Symptoms

Clinical Causes: Contaminated food, especially undercooked ground beef, unpasteurized milk, and contaminated vegetables Ingestion of contaminated water or contact with infected animals Person-to-person transmission through poor hygiene practices Inadequate sanitation practices in food handling

Key Symptoms: Severe abdominal cramps Watery or bloody diarrhea Nausea and vomiting Fever (sometimes mild or absent) In some cases, development of Hemolytic Uremic Syndrome (HUS), leading to kidney failure

Diagnostic & Treatment

Diagnosis Path: Diagnosis typically involves stool tests to detect the presence of E. coli O157:H7 and to identify the production of Shiga toxin. Laboratory analysis confirming the bacteria's serotype and toxin production helps determine the appropriate course of action. Additional tests may include blood tests and kidney function assessments if complications are suspected.

Treatment Protocols: Management focuses on supportive care, such as staying well-hydrated and resting. Antibiotics are generally not recommended as they may increase the risk of complications. Severe cases, especially those progressing to HUS, require hospitalization, kidney support, and close medical supervision. Preventive strategies include proper food handling, cooking meat thoroughly, avoiding unpasteurized products, and practicing good personal hygiene.

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

Clinical Advice & FAQs

Billing Guidance

Is B96.21 a billable ICD-10 code?
Yes, B96.21 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.

Documentation

How do I report B96.21?
Clinical documentation must specify the nature of Shiga toxin-producing Escherichia coli [E. coli] [STEC] O157 as the cause of diseases classified elsewhere and any associated comorbidities for accurate reporting.

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