K71.3

Clinical Causes: Prolonged exposure to hepatotoxic chemicals and substances such as acetaminophen, industrial solvents, or certain medications. Chronic alcohol consumption, which can cause liver inflammation and accentuate toxicity effects. Exposure to environmental toxins, including pesticides and industrial pollutants. Use of herbal supplements or traditional remedies containing hepatotoxic ingredients. Unrecognized or untreated viral infections that may exacerbate liver inflammation in toxic settings.

Key Symptoms: Persistent fatigue and general weakness Loss of appetite and unintentional weight loss Nausea and occasional vomiting Abdominal discomfort or pain particularly in the upper right side Jaundice, characterized by yellowing of the skin and eyes Dark urine and pale stools Swelling in the abdomen (ascites) and legs due to fluid retention Itching and skin rashes in some cases

Diagnosis Path: Blood tests to evaluate liver function, including ALT, AST, alkaline phosphatase, bilirubin, and albumin levels Serological tests to exclude viral hepatitis Imaging studies such as ultrasound, CT scan, or MRI to assess liver structure and identify damage Liver biopsy in select cases to confirm inflammation and evaluate the extent of damage

Treatment Protocols: Elimination of known hepatotoxic substances from the patient’s environment and medication regimen Supportive care with adequate nutrition and hydration Medications to manage symptoms or reduce inflammation, as advised by healthcare providers Monitoring liver function over time to assess progression or improvement In some cases, hospitalization may be necessary to manage severe symptoms or complications Lifestyle modifications such as abstaining from alcohol and adopting a balanced diet