H44.002

Clinical Causes: Bacterial or fungal infections following eye surgery or trauma Spread of infection from neighboring tissues or systemic infections Poorly controlled eye infections leading to secondary endophthalmitis Contamination from contaminated intraocular injections or medical instruments Delayed treatment of conjunctivitis or keratitis

Key Symptoms: Severe eye pain and tenderness Redness and swelling of the eyelids and conjunctiva Decrease in visual acuity or sudden vision loss Floaters or the perception of pulsing or flashing lights Increased sensitivity to light (photophobia) Sudden onset of a cloudy or hazy appearance of the eye Possible discharge or pus within the eye

Diagnosis Path: Diagnosis of purulent endophthalmitis involves a comprehensive eye examination by an ophthalmologist. The evaluation may include: - Slit-lamp examination to assess the anterior segment and view the internal structures of the eye - B-scan ultrasonography to visualize the vitreous and retina when the view is obstructed - Cultures of intraocular fluids, such as vitreous or aqueous humor, to identify the infectious organism - Additional imaging tests if systemic infection is suspected Early diagnosis is critical to preventing irreversible damage and preserving vision.

Treatment Protocols: Treating unspecified purulent endophthalmitis generally requires urgent medical intervention, which may include: - Intravitreal injections of antibiotics or antifungal medications directly into the eye - Systemic antibiotics or antifungal therapies to control systemic spread - Corticosteroids to reduce inflammation and tissue damage - Surgical procedures such as vitrectomy to remove infected vitreous material and debris - Close monitoring of visual function and intraocular pressure Prompt and aggressive treatment is vital in managing the infection, preventing complications, and reducing the risk of permanent vision loss.