D82.0
Wiskott-Aldrich syndrome
Clinical Classification Guidelines
Inclusion Terms
- Immunodeficiency with thrombocytopenia and eczema
Medical Intelligence & Overview
Wiskott-Aldrich syndrome is a rare inherited disorder that primarily affects males. It is characterized by a combination of immune deficiency, low platelet count (thrombocytopenia), and eczema. This condition is part of a group of genetic disorders affecting the immune system, leading to increased susceptibility to infections and other health challenges.
Causes & Symptoms
Clinical Causes: Genetic mutation in the WAS gene on the X chromosome Inheritance pattern: X-linked recessive, meaning the defective gene is passed from mother to son Absence or dysfunction of Wiskott-Aldrich syndrome protein (WASP) affects immune cell function
Key Symptoms: Frequent bacterial, viral, and fungal infections due to immune deficiency Eczema, often severe and persistent Bleeding tendencies from small blood vessel fragility leading to easy bruising and petechiae Low platelet count (thrombocytopenia), which may cause nosebleeds, gum bleeding, or heavy menstrual periods Poor growth and delayed development in some cases Increased risk of autoimmune disorders and certain cancers, such as lymphoma
Diagnostic & Treatment
Diagnosis Path: Diagnosis of Wiskott-Aldrich syndrome involves a combination of clinical evaluation and laboratory tests, including:
Treatment Protocols: While there is no cure for Wiskott-Aldrich syndrome, treatment aims to manage symptoms, prevent infections, and improve quality of life:
Clinical Advice & FAQs
Billing Guidance
Is D82.0 a billable ICD-10 code?
Yes, D82.0 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report D82.0?
Clinical documentation must specify the nature of Wiskott-Aldrich syndrome and any associated comorbidities for accurate reporting.
Cite this Clinical Reference