D59.31
Infection-associated hemolytic-uremic syndrome
Clinical Classification Guidelines
Use Additional Code
- code to identify associated infection, such as :
- E. coli infection (B96.2-)
- Human immunodeficiency virus [HIV] disease (B20)
- Pneumococcal meningitis (G00.1)
- Pneumococcal pneumonia (J13)
- Sepsis due to Streptococcus pneumoniae (A40.3)
- Shigella dysenteriae (A03.9)
- Streptococcus pneumoniae as the cause of diseases classified elsewhere (B95.3)
Inclusion Terms
- Shiga toxin-producing E. coli [STEC] related hemolytic uremic syndrome
- Typical hemolytic uremic syndrome
Medical Intelligence & Overview
Infection-associated hemolytic-uremic syndrome (HUS) is a rare but serious condition that affects the blood and blood vessels, primarily impacting the kidneys. Recognized by its link to specific infections, especially those caused by Shiga toxin-producing bacteria, this syndrome leads to the destruction of blood cells and can cause kidney failure. Prompt recognition and management are essential for a better outcome.
Causes & Symptoms
Clinical Causes: Infections with Shiga toxin-producing *Escherichia coli* (STEC), especially strains like E. coli O157:H7 Other bacterial infections that produce toxins similar to Shiga toxin Less commonly, certain viral infections or medications can also trigger hemolytic-uremic syndrome
Key Symptoms: Abdominal cramps and severe diarrhea, often bloody Fatigue and weakness due to anemia Pale skin and jaundice (yellowing of the skin and eyes) Decreased urine output or swelling due to kidney impairment Fever, nausea, or vomiting in some cases Bruising or bleeding caused by low platelet count
Diagnostic & Treatment
Diagnosis Path: Diagnosis typically involves blood and urine tests to detect anemia, low platelet count, and signs of kidney dysfunction. Additional tests, such as stool cultures and toxin assays, can identify the presence of STEC bacteria. Imaging studies may be used to assess kidney health, and a thorough medical history and physical examination are vital for accurate diagnosis.
Treatment Protocols: Management of infection-associated HUS focuses on supportive care, including fluid management, blood transfusions if needed, and dialysis in cases of severe kidney failure. Antibiotics are generally avoided in cases of STEC infection, as they might increase toxin release. Close monitoring in a hospital setting is often necessary to address complications promptly. Recovery can take weeks, and some individuals may experience lasting kidney damage.
Clinical Advice & FAQs
Billing Guidance
Is D59.31 a billable ICD-10 code?
Yes, D59.31 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report D59.31?
Clinical documentation must specify the nature of Infection-associated hemolytic-uremic syndrome and any associated comorbidities for accurate reporting.
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