E78.2
Mixed hyperlipidemia
Clinical Classification Guidelines
Inclusion Terms
- Broad- or floating-betalipoproteinemia
- Combined hyperlipidemia NOS
- Elevated cholesterol with elevated triglycerides NEC
- Fredrickson's hyperlipoproteinemia, type IIb or III
- Hyperbetalipoproteinemia with prebetalipoproteinemia
- Hypercholesteremia with endogenous hyperglyceridemia
- Hyperlipidemia, group C
- Tubo-eruptive xanthoma
- Xanthoma tuberosum
Excludes Type 1
- cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)
- familial combined hyperlipidemia (E78.49)
Medical Intelligence & Overview
Mixed hyperlipidemia, also known by the ICD-10 code E78.2, is a condition characterized by elevated levels of both cholesterol and triglycerides in the blood. It is often part of broader lipid disorders affecting the body's ability to regulate fats, leading to increased risk of cardiovascular disease. The condition may present with various physical signs and is influenced by multiple factors, both genetic and lifestyle-related.
Causes & Symptoms
Clinical Causes: Genetic factors, such as familial hyperlipidemia Unhealthy dietary habits, including high intake of saturated fats and sugars Obesity and lack of physical activity Underlying medical conditions like hypothyroidism or diabetes mellitus Certain medications that affect lipid metabolism Excessive alcohol consumption
Key Symptoms: Often asymptomatic in early stages Xanthomas: fatty deposits under the skin, such as tuberous and eruptive types Increased risk of cardiovascular issues, which may lead to chest pain or heart attacks Potential for fatty deposits in tendons (tendinous xanthomas) Possible early signs include paleness and fatigue related to cardiovascular stress
Diagnostic & Treatment
Diagnosis Path: Diagnosis involves blood tests to measure lipid levels, including total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides. Medical history and physical examination are important, especially looking for signs like xanthomas. Additional imaging or testing may be recommended to evaluate the extent of arterial involvement or underlying causes.
Treatment Protocols: Managing mixed hyperlipidemia typically includes lifestyle modifications such as adopting a balanced diet low in saturated fats and sugars, engaging in regular physical activity, maintaining a healthy weight, and abstaining from tobacco and excessive alcohol. Pharmacological treatments like statins, fibrates, or other lipid-lowering agents may be prescribed based on individual risk profiles and lipid levels. Regular monitoring of blood lipid levels is essential for adjusting treatment plans.
Clinical Advice & FAQs
Billing Guidance
Is E78.2 a billable ICD-10 code?
Yes, E78.2 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report E78.2?
Clinical documentation must specify the nature of Mixed hyperlipidemia and any associated comorbidities for accurate reporting.
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