P02.7

Clinical Causes: Bacterial infection crossing the membranes from the vagina or cervix Premature rupture of membranes Prolonged labor Multiple vaginal examinations during labor Maternal infections or colonization with pathogenic bacteria Use of internal monitors during labor History of sexually transmitted infections

Key Symptoms: Fever in the mother during labor Increased maternal heart rate Foul-smelling amniotic fluid Uterine tenderness or abnormal uterine tenderness Maternal chills or chills with fever Signs of infection in the newborn such as irritability Respiratory distress in the infant Poor feeding or lethargy in the newborn Temperature instability in the newborn Rapid breathing or difficulty breathing Pontential signs of sepsis, such as low blood pressure

Diagnosis Path: Diagnosis involves a combination of clinical assessment and laboratory tests. Healthcare providers may look for signs of infection in the mother during labor, including fever and uterine tenderness. In newborns, symptoms like respiratory issues, lethargy, and feeding difficulties prompt further testing. Laboratory analysis of amniotic fluid, blood cultures, and placental pathology help confirm the presence of infection. Additional diagnostics may include blood tests such as complete blood count (CBC) and C-reactive protein (CRP) levels. Ultrasound imaging might be used in certain cases to assess fetal well-being.

Treatment Protocols: Treatment typically involves prompt administration of antibiotics to the mother during labor to address the infection and reduce transmission risk to the baby. The newborn may require hospital admission for close monitoring and supportive care, such as respiratory support or antibiotics if infection is suspected. Managing chorioamnionitis is critical to prevent complications such as preterm birth, neonatal sepsis, or long-term developmental issues. The care plan is tailored based on the severity of the infection and the baby’s overall health condition.