N02.6
Recurrent and persistent hematuria with dense deposit disease
Clinical Classification Guidelines
Inclusion Terms
- Recurrent and persistent hematuria with C3 glomerulopathy with dense deposit disease
- Recurrent and persistent hematuria with membranoproliferative glomerulonephritis, type 2
Medical Intelligence & Overview
Recurrent and persistent hematuria refers to the repeated presence of blood in the urine over a period of time. When this condition is associated with dense deposit disease, a form of C3 glomerulopathy, it indicates an ongoing problem affecting the kidneys' filtering units. This condition is classified under ICD-10 code N02.6 and involves complex kidney pathology that can impact overall kidney health and function.
Causes & Symptoms
Clinical Causes: Abnormal immune responses leading to complement system activation Genetic mutations affecting complement regulation Underlying autoimmune conditions Certain infections that provoke immune reactions Other glomerular diseases such as membranoproliferative glomerulonephritis type 2
Key Symptoms: Blood in the urine (hematuria), which may be visible or detectable only under a microscope Foamy or cola-colored urine due to blood or protein content Swelling or edema, especially in the legs, ankles, or around the eyes High blood pressure Possible decreased urine output in advanced cases Fatigue or general feeling of unwellness
Diagnostic & Treatment
Diagnosis Path: Urinalysis to detect blood, protein, and cellular components in urine Blood tests evaluating kidney function and immune system markers Complement levels (such as C3 and C4) measurement to assess immune activity Kidney biopsy to examine tissue under a microscope for dense deposits and glomerular changes Immunofluorescence microscopy to identify immune complex deposits
Treatment Protocols: Medications to control blood pressure, such as ACE inhibitors or ARBs Immunosuppressive drugs to reduce immune system activity and immune complex formation Plasma exchange therapies in severe cases to remove harmful antibodies Monitoring kidney function regularly to assess disease progression Supportive care including dietary modifications and managing symptoms In some cases, dialysis or kidney transplantation may be necessary if kidney failure develops
Clinical Advice & FAQs
Billing Guidance
Is N02.6 a billable ICD-10 code?
Yes, N02.6 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report N02.6?
Clinical documentation must specify the nature of Recurrent and persistent hematuria with dense deposit disease and any associated comorbidities for accurate reporting.
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