ICD-10-CM Billable Code

B27.82

Other infectious mononucleosis with meningitis

Clinical Classification Guidelines

Medical Intelligence & Overview

Infectious mononucleosis, commonly known as mono or the 'kissing disease,' is caused by the Epstein-Barr virus (EBV). While mono typically results in symptoms like fatigue and sore throat, in some cases, it can lead to more serious complications such as meningitis, which is inflammation of the membranes surrounding the brain and spinal cord. The ICD-10 code B27.82 specifically classifies cases where infectious mononucleosis is complicated by meningitis. Recognizing the signs and understanding the nature of this condition are essential for appropriate medical management and care.

Causes & Symptoms

Clinical Causes: Infection with Epstein-Barr virus (EBV), the primary cause of infectious mononucleosis. Rarely, other viruses such as cytomegalovirus or HIV may cause similar symptoms, but EBV is the most common. The virus spreads through saliva, which explains the nickname 'kissing disease,' but it can also be transmitted through sharing drinks, utensils, or close contact. Development of meningitis in mono cases, although uncommon, may result from the virus spreading to the meninges or secondary bacterial infections.

Key Symptoms: Fever Sore throat, often severe with swollen tonsils Swollen lymph nodes in the neck and armpits Fatigue and general tiredness Muscle aches Headache Skin rash Enlarged spleen or liver in some cases Signs of meningitis, which may include: Severe headache Stiff neck Sensitivity to light (photophobia) Nausea or vomiting Altered mental status or confusion

Diagnostic & Treatment

Diagnosis Path: Diagnosis involves a combination of clinical evaluation and laboratory tests. Doctors typically perform blood tests to detect atypical lymphocytes and specific antibodies produced in response to EBV. A monospot test may be used for quick detection, although it can sometimes give false negatives. Cerebrospinal fluid analysis via lumbar puncture is necessary to confirm meningitis, revealing inflammation and possibly identifying the infectious agent. Imaging studies like MRI or CT scans may assist in evaluating complications or ruling out other causes.

Treatment Protocols: There is no specific antiviral treatment for EBV infection; management focuses on relieving symptoms. Rest, adequate hydration, and over-the-counter pain relievers can help reduce discomfort. In cases complicated by meningitis, hospitalization may be necessary for close monitoring and supportive care. Antibiotics are not effective against viruses, but may be used if a secondary bacterial infection occurs. Preventative measures include good hygiene practices and avoiding close contact with infected individuals. Recovery can take several weeks, especially if complications like meningitis develop.

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

Clinical Advice & FAQs

Billing Guidance

Is B27.82 a billable ICD-10 code?
Yes, B27.82 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.

Documentation

How do I report B27.82?
Clinical documentation must specify the nature of Other infectious mononucleosis with meningitis and any associated comorbidities for accurate reporting.

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