T43.223

Clinical Causes: Accidental overdose due to misunderstanding medication instructions. Intentional overdose or self-harm attempts involving SSRIs. Misuse or abuse of the medication, such as taking higher doses than prescribed. Concomitant use of other substances that may increase toxicity. Drug interactions that lead to increased serum levels of SSRIs.

Key Symptoms: Nausea and vomiting Dizziness or lightheadedness Rapid heartbeat (tachycardia) Serious changes in mental state, such as agitation or confusion Muscle tremors or twitching Seizures High fever Loss of coordination or difficulty walking Dilated pupils Severe cases may lead to coma or life-threatening complications

Diagnosis Path: Healthcare professionals diagnose SSRI poisoning based on a combination of medical history, including medication use, and physical examination. Laboratory tests like blood tests can measure drug levels and check for complications such as electrolyte imbalances or kidney issues. In some cases, additional investigations may be needed to rule out other conditions or identify co-occurring factors.

Treatment Protocols: Treatment focuses on stabilizing the patient's condition and removing or reducing the toxin's effects. Common approaches include: - Supportive care such as monitoring vital signs and ensuring airway, breathing, and circulation are maintained. - Activated charcoal may be administered to absorb the drug if ingestion was recent. - Intravenous fluids to prevent dehydration and support blood pressure. - Medications to control symptoms like seizures or abnormal heart rhythms. - In severe cases, hospitalization might be necessary, including interventions such as gastric lavage or dialysis. Psychiatric assessment and counseling may follow to address underlying issues and prevent future incidents.