M35.02

Clinical Causes: Autoimmune response where the immune system attacks moisture-producing glands and lung tissue Genetic predisposition which may make some individuals more susceptible Environmental factors such as viral infections, which can trigger or exacerbate symptoms Hormonal influences, particularly in women, as the syndrome is more prevalent among females Potentially, other connective tissue diseases may coexist, complicating the clinical picture

Key Symptoms: Dryness of the eyes and mouth Persistent dry cough Shortness of breath, especially during exertion Lung inflammation leading to symptoms like chest tightness or pain Fatigue and general discomfort Recurrent respiratory infections Swelling or inflammation around the lungs

Diagnosis Path: Medical history assessment, focusing on dry eyes, dry mouth, and respiratory symptoms Blood tests to detect autoimmune markers such as ANA, anti-SSA, and anti-SSB antibodies Schirmer’s test or eye staining to evaluate tear production and eye dryness Salivary gland biopsies may be conducted to look for lymphocytic infiltration High-resolution CT scans of the chest to identify lung involvement such as inflammation or fibrosis Pulmonary function tests to quantify lung capacity and airflow limitations

Treatment Protocols: Artificial tears and saliva substitutes to alleviate dryness Anti-inflammatory medications such as corticosteroids for lung inflammation Immunosuppressive drugs in more severe cases to modulate the immune response Regular pulmonary function monitoring to assess lung health Treating associated conditions like infections promptly Lifestyle modifications, including smoking cessation and avoiding lung irritants Physical therapy and breathing exercises to improve lung function