D81.7
Major histocompatibility complex class II deficiency
Clinical Classification Guidelines
Medical Intelligence & Overview
Major Histocompatibility Complex Class II Deficiency, also known as MHC II deficiency, is a rare genetic disorder that affects the immune system. Individuals with this condition have difficulty fighting off infections because their immune response is compromised. The deficiency specifically impacts the development and function of certain immune cells, leading to increased susceptibility to a wide range of infections.
Causes & Symptoms
Clinical Causes: Genetic mutation inherited in an autosomal recessive pattern Defects in the genes responsible for the development of MHC class II molecules Lack of proper expression of these molecules on the surface of antigen-presenting cells
Key Symptoms: Repeated bacterial, viral, and fungal infections Persistent or severe infections that are difficult to treat Failure to thrive in infants and young children Recurrent respiratory infections Chronic diarrhea Skin infections and rashes Poor wound healing
Diagnostic & Treatment
Diagnosis Path: Diagnosis involves a combination of clinical evaluation and laboratory tests. These may include:
Treatment Protocols: While there is no specific cure for MHC II deficiency, management strategies aim to strengthen the immune system and prevent complications:
Clinical Advice & FAQs
Billing Guidance
Is D81.7 a billable ICD-10 code?
Yes, D81.7 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report D81.7?
Clinical documentation must specify the nature of Major histocompatibility complex class II deficiency and any associated comorbidities for accurate reporting.
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