D68.029
Von Willebrand disease, type 2, unspecified
Clinical Classification Guidelines
Inclusion Terms
- Qualitative defect in von Willebrand factor function, with no further subtyping
Medical Intelligence & Overview
Von Willebrand disease (VWD) is a common bleeding disorder caused by a defect or deficiency of a specific protein called von Willebrand factor (VWF). This protein plays a crucial role in blood clotting, helping blood cells stick together to form clots and stop bleeding. Type 2 VWD, unspecified, indicates a qualitative defect where the function of VWF is impaired, but without further classification into subtypes. Individuals with this condition may experience prolonged bleeding after injuries, surgeries, or other medical procedures. Understanding the nature of this disorder can help in managing symptoms and preventing complications.
Causes & Symptoms
Clinical Causes: Genetic mutations inherited from family members, often following an autosomal dominant pattern Alterations in the structure or function of von Willebrand factor that impair its ability to facilitate clot formation Rarely, acquired conditions affecting VWF levels or function, though these are not related to the genetic subtype
Key Symptoms: Frequent or prolonged nosebleeds Bleeding gums during dental procedures or regular oral hygiene Easy bruising from minor injuries Heavy or prolonged menstrual bleeding in women Bleeding after minor cuts or injuries Bleeding episodes after surgical procedures or dental work In some cases, internal bleeding, such as hemarthrosis (bleeding into joints) or gastrointestinal bleeding
Diagnostic & Treatment
Diagnosis Path: Complete blood count (CBC) to evaluate overall blood health Von Willebrand factor antigen test to measure VWF levels Ristocetin cofactor activity assay to assess how well VWF functions in clot formation Factor VIII activity test, since VWF stabilizes this clotting factor Bleeding time test to evaluate platelet function and blood clotting ability
Treatment Protocols: Desmopressin (DDAVP), a medication that stimulates the release of VWF from storage sites in blood vessels, effective for many patients with type 2 VWD Replacement therapies, such as infusions of VWF concentrates, especially during surgeries or severe bleeding episodes Antifibrinolytic medications like tranexamic acid to reduce bleeding in mucous membranes Careful planning for surgeries or dental procedures, including pre-treatment with appropriate hemostatic agents Avoiding medications that impair platelet function, such as aspirin and non-steroidal anti-inflammatory drugs (NSAIDs)
Clinical Advice & FAQs
Billing Guidance
Is D68.029 a billable ICD-10 code?
Yes, D68.029 is a specific, billable code that can be used to indicate a diagnosis for reimbursement purposes.
Documentation
How do I report D68.029?
Clinical documentation must specify the nature of Von Willebrand disease, type 2, unspecified and any associated comorbidities for accurate reporting.
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